Prostaglandin D2, HDP1 and CRTH2 receptor agonist (ab120888)
Key features and details
- High affinity DP1 and CRTH2 receptor agonist. Major prostaglandin produced by mast cells.
- CAS Number: 41598-07-6
- Purity: > 99%
- Soluble in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Prostaglandin D2, HDP1 and CRTH2 receptor agonist -
Description
High affinity DP1 and CRTH2 receptor agonist. Major prostaglandin produced by mast cells. -
Alternative names
- PGD2
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Biological description
High affinity DP1 receptor agonist (Ki = 21 nM). Able to bind to the CRTH2 receptor (Ki = 2.4 nM). Major prostaglandin produced by mast cells in allergic disease. Capable of recruiting other inflammatory cells including eosinophils and basophils. -
Purity
> 99% -
CAS Number
41598-07-6 -
Chemical structure
Properties
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Chemical name
(5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid -
Molecular weight
352.47 -
Molecular formula
C20H32O5 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1C/C=CCCCC(=O)O -
Source
Synthetic
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Research areas