PNU 282987, alpha7 nAChR agonist (ab120558)
Key features and details
- Selective α7 nAChR agonist
- CAS Number: 123464-89-1
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PNU 282987, alpha7 nAChR agonist -
Description
Selective α7 nAChR agonist -
Biological description
Selective α7nAChR agonist. Negligible activity at α1β1γδ and α3β4 receptors. High affinity for rat α7nACh receptors (Ki = 26 nM). Functional antagonist at 5-HT3 receptors (IC50 = 4541 nM).
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Purity
> 99% -
CAS Number
123464-89-1 -
Chemical structure
Properties
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Chemical name
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride -
Molecular weight
301.22 -
Molecular formula
C14H17ClN2O.HCl -
PubChem identifier
11243536 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CN2CCC1[C@H](C2)NC(=O)C3=CC=C(C=C3)Cl.Cl -
Source
Synthetic
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Research areas
