PKSI-527, plasma kallikrein inhibitor (ab144543)
Key features and details
- Selective plasma kallikrein inhibitor
- CAS Number: 128837-71-8
- Purity: > 95%
- Soluble in water to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PKSI-527, plasma kallikrein inhibitor -
Description
Selective plasma kallikrein inhibitor -
Biological description
Selective plasma kallikrein inhibitor (Ki = 0.81 μM). Synergizes with NO donors. Shows antiarthritic, vasodilatory and antithrombotic effects in vivo. -
Purity
> 95% -
CAS Number
128837-71-8 -
Chemical structure
Properties
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Chemical name
trans-4-Aminomethylcyclohexanecarbonyl-phenylalanyl-4-carboxymethylanilide -
Molecular weight
474.00 -
Molecular formula
C25H31N3O4.HCl -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.NC[C@@H]1CC[C@H](CC1)C(=O)NC(Cc2ccccc2)C(=O)Nc3ccc(CC(=O)O)cc3 -
Source
Synthetic
