Pitstop® 1-25, clathrin inhibitor (ab144651)
Key features and details
- Novel, selective clathrin inhibitor
- CAS Number: 1419321-16-6
- Purity: > 99%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pitstop® 1-25, clathrin inhibitor -
Description
Novel, selective clathrin inhibitor -
Biological description
Novel, selective clathrin inhibitor. Inhibits the clathrin terminal domain (IC50 = 6.9 μM). No inhibition seen with dynamin and other key clathrin mediated endocytosis pathway proteins. Low cell permeability. Related products Pitstop® 2 (ab120687), Pitstop® 1 (ab120686) and Pitstop® 2-100 (ab144650).
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Purity
> 99% -
General notes
Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Pitstop® is a trademark of Freie Universitat Berlin, Newcastle Innovation Ltd. and Children's Medical Research Institute -
CAS Number
1419321-16-6 -
Chemical structure
Properties
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Chemical name
3-Sulfo-N-(benzyl)-1,8-naphthalimide potassium salt -
Molecular weight
405.47 -
Molecular formula
C19H12KNO5S -
PubChem identifier
75593424 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=S(=O)(O[K])c2cc1cccc4c1c(c2)C(=O)N(Cc3ccccc3)C4=O -
Source
Synthetic
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Research areas
