Pirfenidone, orally active anti-inflammatory antifibrotic agent (ab141425)
Key features and details
- Orally active anti-inflammatory antifibrotic agent
- CAS Number: 53179-13-8
- Purity: > 99%
- Soluble in 1 eq. HCl to 100 mM and in water to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pirfenidone, orally active anti-inflammatory antifibrotic agent -
Description
Orally active anti-inflammatory antifibrotic agent -
Biological description
Orally active anti-inflammatory, antifibrotic and antiproliferative agent. Blood-brain barrier permeable. Shown to modulate cytokines TGF-β and TNF-α.
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Purity
> 99% -
CAS Number
53179-13-8 -
Chemical structure
Properties
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Chemical name
5-Methyl-1-phenyl-2(1H)-pyridinone -
Molecular weight
185.23 -
Molecular formula
C12H11NO -
PubChem identifier
40632 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 1 eq. HCl to 100 mM and in water to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC2=CN(c1ccccc1)C(=O)C=C2 -
Source
Synthetic
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Research areas