DIF-1, cell proliferation inhibitor (ab141638)
Key features and details
- Morphogen. Inhibits cancer cell line proliferation and induces cell differentiation.
- CAS Number: 111050-72-7
- Purity: > 98%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
DIF-1, cell proliferation inhibitor -
Description
Morphogen. Inhibits cancer cell line proliferation and induces cell differentiation. -
Alternative names
- Differentiation-inducing factor-1
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Biological description
Morphogen that induces differentiation of Dictyostelium discoideum. Inhibits proliferation of cancer cell lines by suppressing Wnt/ β-catenin signaling pathway. Also induces tumor cell differentiation. -
Purity
> 98% -
CAS Number
111050-72-7 -
Chemical structure
Properties
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Chemical name
1-(3,5-Dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one -
Molecular weight
307.20 -
Molecular formula
C13H16Cl2O4 -
PubChem identifier
123886 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCC(=O)C1=C(C(=C(C(=C1O)Cl)OC)Cl)O -
Source
Synthetic
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Research areas