CK 666, Actin polymerization inhibitor (ab141231)
Key features and details
- Potent inhibitor of actin polymerization
- CAS Number: 442633-00-3
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CK 666, Actin polymerization inhibitor -
Description
Potent inhibitor of actin polymerization -
Biological description
Potent inhibitor of actin polymerization. Inhibits the Arp2/3 (IC50 = 17 μM), SpArp2/3 (IC50 = 5 μM) and HsArp2/3 complexes (IC50= 4 μM) by preventing a shift into an active conformation.
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Purity
> 99% -
CAS Number
442633-00-3 -
Chemical structure
Properties
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Chemical name
2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide -
Molecular weight
296.34 -
Molecular formula
C18H17FN2O -
PubChem identifier
589075 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Fc1ccccc1C(=O)NCCc2c3ccccc3nc2C -
Source
Synthetic
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Research areas
