Pifithrin-alpha-HBr, p53 Inhibitor (ab120478)
Key features and details
- p53 Inhibitor
- CAS Number: 63208-82-2
- Purity: > 95%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pifithrin-alpha-HBr, p53 Inhibitor -
Description
p53 Inhibitor -
Biological description
p53 Inhibitor. Specifically blocks tumor supressor p53 transcriptional activity and can supress heat shock and glucocorticoid signalling pathways. Additionally offers protection to cells from p53 mediated apoptosis. Active in vivo; protects mice from chemotherapy side effects associated with p53 induction. Also aryl hydrocarbon receptor (AHR) agonist.
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Purity
> 95% -
General notes
Pifithrin-?-HBr is light senstive and it is recommended that the compound is protected from light.
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CAS Number
63208-82-2 -
Chemical structure
