Philanthotoxin-7,4 (PhTx-74) (mM/ml), GluA1/GluA2 (formerly GluR1/2) inhibitor (ab146706)
Key features and details
- GluA1/GluA2 (formerly GluR1/2) inhibitor. 1 ml water soluble pack.
- CAS Number: 401601-12-5
- Purity: > 98%
- Soluble in 1ml of water to give specified mM/ml concentration
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Philanthotoxin-7,4 (PhTx-74) (mM/ml), GluA1/GluA2 (formerly GluR1/2) inhibitor -
Description
GluA1/GluA2 (formerly GluR1/2) inhibitor. 1 ml water soluble pack. -
Alternative names
- PhTx-74
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Biological description
A subtype-selective, use-dependent inhibitor of native AMPA receptors. Inhibits GluA1/A2 (formerly GluR1/2), with little activity at GluA2/A3 (formerly GluR2/3)
Soluble in 1 ml water to give specified mM/ml concentration. Find out more. -
Purity
> 98% -
CAS Number
401601-12-5 -
Chemical structure
Properties
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Chemical name
(S)-N-[7-[(4-Aminobutyl)amino]heptyl]-4-hydroxy-a-[(1-oxobutyl)amino]benzenepropanamide dihydrochloride -
Molecular weight
507.54 -
Molecular formula
C24H42N4O3.2HCl -
PubChem identifier
46213501 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 1ml of water to give specified mM/ml concentration -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.Cl.Oc1ccc(C[C@H](NC(=O)CCC)C(=O)NCCCCCCCNCCCCN)cc1 -
Source
Synthetic
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Research areas
