Phentolamine mesylate, alpha-AR antagonist (ab143253)
Key features and details
- Potent, competitive and reversible non-selective α-AR antagonist
- CAS Number: 65-28-1
- Purity: > 99%
- Soluble in water to 100 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Phentolamine mesylate, alpha-AR antagonist -
Description
Potent, competitive and reversible non-selective α-AR antagonist -
Biological description
Potent, competitive and reversible non-selective α-adrenoceptor antagonist. Inhibits agonist-induced smooth muscle contractions (IC50 = 5-30 nM). Shows vasodilatory, positive inotropic, chronotropic and antihypertensive effects in vivo.
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Purity
> 99% -
CAS Number
65-28-1 -
Chemical structure
Properties
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Chemical name
3-[[(4,5-Dihydro-1H-imidazol-2-ylmethyl)](4-methylphenyl)amino]phenol mesylate -
Molecular weight
377.46 -
Molecular formula
C17H19N3O.CH3SO3H -
PubChem identifier
91430 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.CS(=O)(=O)O -
Source
Synthetic
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Research areas