PD 173212, N-type voltage-gated Ca2+ channel blocker (ab141832)
Key features and details
- Potent, selective N-type voltage-gated Ca2+ channel blocker
- CAS Number: 217171-01-2
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PD 173212, N-type voltage-gated Ca2+ channel blocker -
Description
Potent, selective N-type voltage-gated Ca2+ channel blocker -
Biological description
Potent, selective N-type voltage-gated Ca2+ channel blocker (IC50 = 36 nM). Selectivity over K+, Na+ and L-type Ca2+ channels. Shows anticonvulsant effects in vivo. -
Purity
> 99% -
CAS Number
217171-01-2 -
Chemical structure
Properties
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Chemical name
(2S)-N-[(2S)-1-(tert-Butylamino)-1-oxo-3-(4-phenylmethoxyphenyl)propan-2-yl]-2-[(4-tert-butylphenyl)methyl-methylamino]-4-methylpentanamide -
Molecular weight
599.90 -
Molecular formula
C38H53N3O3 -
PubChem identifier
9916734 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)CC(C(=O)NC(CC1=CC=C(C=C1)OCC2=CC=CC=C2)C(=O)NC(C)(C)C)N(C)CC3=CC=C(C=C3)C(C)(C)C -
Source
Synthetic
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Research areas