Paroxetine hydrochloride, 5-HT uptake inhibitor (ab120069)
Key features and details
- 5-HT uptake inhibitor
- CAS Number: 110429-35-1
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Paroxetine hydrochloride, 5-HT uptake inhibitor -
Description
5-HT uptake inhibitor -
Biological description
Potent, selective 5-HT (serotonin) uptake inhibitor. Inhibits human and rat 5-HT transporters (Ki values are 0.065 and 0.05 nM, respectively). Antidepressant and anxiolytic in vivo.
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Purity
> 99% -
CAS Number
110429-35-1 -
Chemical structure
Properties
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Chemical name
(3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine hydrochloride -
Molecular weight
365.83 -
Molecular formula
C19H20FNO3.HCl -
PubChem identifier
62878 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.Cl -
Source
Synthetic
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Research areas