Oridonin, anti-tumor agent (ab142094)
Key features and details
- Antitumor agent. Cell-permeable.
- CAS Number: 28957-04-2
- Purity: > 97%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Oridonin, anti-tumor agent -
Description
Antitumor agent. Cell-permeable. -
Biological description
Antitumor agent (IC50 = 7.4 μM). Shows apoptotic, antiangiogenic and antiproliferative activity in vitro. Inhibits NF-κB activity and downregualtes BCL-xL. Active in vivo. Cell-permeable. -
Purity
> 97% -
CAS Number
28957-04-2 -
Chemical structure
Properties
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Chemical name
(1S,4aR,5S,6S,14S)-1,5,6,14-Tetrahydroxy-4,4-dimethyl-8-methylenedecahydro-1H-6,11b-(epoxymethano)-6a,9-methanocyclohepta[a]naphthalen-7(8H)-one -
Molecular weight
364.43 -
Molecular formula
C20H28N5O6 -
PubChem identifier
457846 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C -
Source
Synthetic
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Research areas
