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NK-3R peptide (ab176411)

Key features and details

  • Suitable for: Blocking

Description

  • Product name

    NK-3R peptide

  • Animal free

    No

  • Nature

    Synthetic

Preparation and Storage

  • Alternative names

    • MGC148060
    • MGC148061
    • Neurokinin B receptor
    • Neurokinin beta receptor
    • Neuromedin K Receptor
    • Neuromedin-K receptor
    • NK 3 receptor
    • NK 3R
    • NK-3 receptor
    • NK-3R
    • NK3 receptor
    • NK3R
    • NK3R_HUMAN
    • NKR
    • TAC 3R
    • TAC3R
    • TAC3RL
    • Tachykinin receptor 3
    • TACR 3
    • Tacr3
    see all

  • Function

    This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.

  • Involvement in disease

    Hypogonadotropic hypogonadism 11 with or without anosmia

  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.

  • Post-translational
    modifications

    The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue.

  • Cellular localization

    Cell membrane.
  • Information by UniProt

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