Necrostatin-1, inactive control, N-demethylated thiohydantoin analog of Necrostatin-1 (ab145889)
Key features and details
- Cell-permeable N-demethylated thiohydantoin analog of Necrostatin-1 (ab141053) without antinecroptotic properties
- CAS Number: 64419-92-7
- Purity: > 95%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Necrostatin-1, inactive control, N-demethylated thiohydantoin analog of Necrostatin-1 -
Description
Cell-permeable N-demethylated thiohydantoin analog of Necrostatin-1 (ab141053) without antinecroptotic properties -
Alternative names
- 5-((1H-indol-3-yl)methyl)-2-thioxoimidazolidin-4-one
- 5-(Indol-3-ylmethyl)-2-thiohydantoin
- Nec-1i
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Biological description
Cell-permeable N-demethylated thiohydantoin analog of Necrostatin-1 (Nec-1) (ab141053) without antinecroptotic properties; serves as an inactive control.
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Purity
> 95% -
General notes
This inactive inhibitor of necrosis should not be used in high concentration.
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CAS Number
64419-92-7 -
Chemical structure
Properties
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Chemical name
5-(Indol-3-ylmethyl)-2-thiohydantoin -
Molecular weight
245.30 -
Molecular formula
C12H11N3OS -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
