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NECA, adenosine agonist (ab120440)

Price and availability

110 563 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Highly potent adenosine agonist
  • CAS Number: 35920-39-9
  • Purity: > 98%
  • Soluble in DMSO to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    NECA, adenosine agonist
  • Description

    Highly potent adenosine agonist
  • Biological description

    Potent agonist of adenosine receptors, non-selective analog of adenosine (Ki values are 14 (A1), 20 (A2A), 330 (A2B), and 6.2 nM (A3)). Offers cardio-protection by limiting infarction in situ.

  • Purity

    > 98%
  • CAS Number

    35920-39-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide
  • Molecular weight

    308.30
  • Molecular formula

    C12H16N6O4
  • PubChem identifier

    448222
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O
  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Apoptosis
    • Receptors
    • Associated Proteins
    • Cardiovascular
    • Hypoxia
    • Hypoxia-Regulated
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • More GPCR
    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Cardiovascular
    • Blood
    • Coagulation
    • Regulatory
    • Cell Biology
    • Apoptosis
    • Phagocytosis
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR
    • Neuroscience
    • Neurology process
    • Neurogenesis
    • Epigenetics and Nuclear Signaling
    • Cardiovascular/Immune
    • Hypoxia
    • Hypoxia regulated
    • Cancer
    • Invasion/microenvironment
    • Hypoxia
    • Hypoxia-related proteins
    • Cardiovascular
    • Atherosclerosis
    • Ischemia / Reperfusion
    • Cardiovascular
    • Atherosclerosis
    • Vascular Inflammation
    • Inflammatory mediators
    • Cardiovascular
    • Heart
    • Cardiac metabolism
    • Cardiovascular
    • Heart
    • Cardiac arrhythmias
    • Neuroscience
    • Neurology process
    • Neuroregeneration
    • Neuroregeneration
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Adenosine
    • Non-selective
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Adenosine
    • Non-selective
    • Agonists
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Purinergics
    • P1
    • Agonists
    • Metabolism
    • Pathways and Processes
    • Metabolism processes
    • Hypoxia
    • Metabolism
    • Pathways and Processes
    • Metabolism processes
    • Apoptosis
    • Metabolism
    • Types of disease
    • Heart disease
    • Biochemicals
    • Research Area
    • Heart disease
    • Adenosine
    • Non-selective
    • Biochemicals
    • Research Area
    • Heart disease
    • Adenosine
    • Non-selective
    • Agonists
    • Biochemicals
    • Research Area
    • Respiratory disease
    • Adenosine
    • Non-selective
    • Biochemicals
    • Research Area
    • Respiratory disease
    • Adenosine
    • Non-selective
    • Agonists
    • Biochemicals
    • Research Area
    • Stroke
    • Adenosine
    • Non-selective
    • Biochemicals
    • Research Area
    • Stroke
    • Adenosine
    • Non-selective
    • Agonists
    • Cancer
    • Cell Death
    • Apoptosis
    • Phagocytosis
    • Cancer
    • Cell Death
    • Apoptosis
    • Receptors
    • Associated Proteins
    • Cancer
    • Cell Death
    • Apoptosis
    • Metabolism

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