Native Human IgG2 protein (ab90284)
Key features and details
- Expression system: Native
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE
-
Product name
Native Human IgG2 protein
See all IgG2 proteins and peptides -
Biological activity
Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 and 2 by FDA approved tests. -
Purity
> 95 % SDS-PAGE. -
Expression system
Native -
Protein length
Full length protein -
Animal free
No -
Nature
Native -
-
Species
Human -
Additional sequence information
Prepared from myeloma plasma.
-
Preparation and Storage
-
Alternative names
- Ig gamma-2 chain C region
- IGHG2
- immunoglobulin Gm2
see all -
Relevance
There are four IgG subclasses (IgG1, 2, 3 and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant). IgG2 is the only IgG subclass which passes through the placenta at a level generally lower than that found in the mother. A deficiency of IgG2 indicates a poor antibody response to bacterial polysaccharides and can lead to increased susceptibility to infections caused by encapsulated bacteria. -
Cellular localization
Secreted
Images
-
SDS-PAGE - Native Human IgG2 protein (ab90284)
SDS PAGE analysis ab90284 under reduced/heated conditions.
Lane 1: LMW Standard;
Lane 2: 5µg ab90284;
Lane 3 10µg ab90284;
Lane 4 20µg ab90284.
