Namoline, lysine-specific demethylase 1 inhibitor (ab144666)
Key features and details
- Selective, reversible lysine-specific demethylase 1 inhibitor
- CAS Number: 342795-11-3
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Namoline, lysine-specific demethylase 1 inhibitor -
Description
Selective, reversible lysine-specific demethylase 1 inhibitor -
Alternative names
- Namolin
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Biological description
Selective, reversible lysine-specific demethylase 1 (LSD1) inhibitor (IC50 = 51 μM). Silences androgen receptor-regulated gene expression. Shows antiproliferative effects in vivo.
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Purity
> 99% -
CAS Number
342795-11-3 -
Chemical structure
Properties
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Chemical name
3-Chloro-6-nitro-2-(trifluoromethyl)-4H-1-benzopyran-4-one -
Molecular weight
293.59 -
Molecular formula
C10H3ClF3NO4 -
PubChem identifier
715694 -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
[O-][N+](=O)c1ccc2OC(=C(Cl)C(=O)c2c1)C(F)(F)F -
Source
Synthetic
