N-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone (ab145219)
Key features and details
- Endogenous lipid anorectic hormone which significantly reduced food intake in a dose-dependent fashion
- CAS Number: 108321-22-8
- Purity: > 98%
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
N-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone -
Description
Endogenous lipid anorectic hormone which significantly reduced food intake in a dose-dependent fashion -
Alternative names
- C16:0 NAPE
- NPPE
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Biological description
Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice without causing taste aversion. Found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations), suggesting that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight, suggesting that NAPE and long-acting NAPE analogs may be novel therapeutic targets for the treatment of obesity.
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Purity
> 98% -
CAS Number
108321-22-8 -
Chemical structure
Properties
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Molecular weight
930.40 -
Molecular formula
C53H104NO9P -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
