N omega-Nitro-L-arginine methyl ester hydrochloride (L-NAME), NOS inhibitor (ab120136)
Key features and details
- NOS inhibitor
- CAS Number: 51298-62-5
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
N omega-Nitro-L-arginine methyl ester hydrochloride (L-NAME), NOS inhibitor -
Description
NOS inhibitor -
Alternative names
- L-NAME
-
Biological description
Cell-permeable NOS inhibitor. More soluble analog of arginine. (pIC50 values are 4.3, 5.7 and 5.6 at human iNOS, nNOA and eNOS, respectively).
-
Purity
> 98% -
CAS Number
51298-62-5 -
Chemical structure
Properties
-
Chemical name
Nω-Nitro-L-arginine methyl ester hydrochloride -
Molecular weight
269.69 -
Molecular formula
C7H15N5O4.HCl -
PubChem identifier
135193 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
Cl.N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(=O)OC -
Source
Synthetic
-
Research areas
- Biochemicals
- Pharmacology
- Signaling
- Signal transduction
- Nitric oxide & oxidative stress
- NOS
- Inhibitors
- Biochemicals
- Research Area
- Alzheimer's Disease
- Signaling
- Signal transduction
- Nitric oxide signaling
- NOS
- Inhibitors
- Biochemicals
- Research Area
- Diabetes
- Signaling
- Signal transduction
- Nitric oxide signaling
- NOS
- Inhibitors
- Biochemicals
- Research Area
- Hypertension
- Signaling
- Signal transduction
- Nitric oxide signaling
- NOS
- Inhibitors
- Biochemicals
- Research Area
- Obesity
- Signaling
- Signal transduction
- Nitric oxide signaling
- NOS
- Inhibitors