Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Suitable for: Blocking

Product name

MTBP peptide
Animal free

No
Nature

Synthetic

Alternative names
- hMTBP
- MDM 2 binding protein
- MDM 2 BP
- MDM2 (mouse double minute 2) binding protein
- MDM2 (mouse double minute 2) binding protein 104kD
- MDM2 binding protein
- MDM2 BP
- Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein
- Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa
- Mdm2 transformed 3T3 cell double minute 2 p53 binding protein binding protein
- Mdm2-binding protein
- MDM2BP
- Mouse double minute 2 homolog binding protein
- MTBP
- MTBP_HUMAN
see all
Function

Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.
Sequence similarities

Belongs to the MTBP family.
Target information above from: UniProt accession Q96DY7 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

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