Astana Biomed Group, an authorized Abcam distributor in Central Asia

MTBP peptide (ab6235)

Key features and details

  • Suitable for: Blocking

Description

  • Product name

    MTBP peptide

  • Animal free

    No

  • Nature

    Synthetic

Preparation and Storage

  • Alternative names

    • hMTBP
    • MDM 2 binding protein
    • MDM 2 BP
    • MDM2 (mouse double minute 2) binding protein
    • MDM2 (mouse double minute 2) binding protein 104kD
    • MDM2 binding protein
    • MDM2 BP
    • Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein
    • Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa
    • Mdm2 transformed 3T3 cell double minute 2 p53 binding protein binding protein
    • Mdm2-binding protein
    • MDM2BP
    • Mouse double minute 2 homolog binding protein
    • MTBP
    • MTBP_HUMAN
    see all

  • Function

    Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.

  • Sequence similarities

    Belongs to the MTBP family.
  • Information by UniProt

Images

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