MSOP, group III metabotropic glutamate receptor antagonist (ab141381)
Key features and details
- Potent, selective group III metabotropic glutamate receptor antagonist
- CAS Number: 66515-29-5
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
MSOP, group III metabotropic glutamate receptor antagonist -
Description
Potent, selective group III metabotropic glutamate receptor antagonist -
Biological description
Potent, selective group III metabotropic glutamate receptor antagonist. Selective inhibition for L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord (KD = 51 μM) compared to the (1S,3S)-ACPD-sensitive presynaptic mGlu (KD > 700 μM). No activity on postsynaptic mGlu receptors or ionotropic glutamate receptors on neonatal rat motoneurons.
Also available in simple stock solutions (ab146735) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS Number
66515-29-5 -
Chemical structure
Properties
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Chemical name
2-Methyl-O-phosphonoserine -
Molecular weight
199.10 -
Molecular formula
C4H10NO6P -
PubChem identifier
3964633 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(N)(COP(=O)(O)O)C(=O)O -
Source
Synthetic
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Research areas
