UCPH-101, Selective EAAT1 inhibitor (ab120309)
Key features and details
- Selective EAAT1 inhibitor
- CAS Number: 1118460-77-7
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
UCPH-101, Selective EAAT1 inhibitor -
Description
Selective EAAT1 inhibitor -
Biological description
Selective inhibitor of EAAT1 (IC50 = 0.67 μM). Displays >400-fold selectivity over EAAT2 and EAAT3.
Blood-brain barrier permeable analog UCPH-102 also available (ab146404). -
Purity
> 98% -
CAS Number
1118460-77-7 -
Chemical structure
Properties
-
Chemical name
2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile -
Molecular weight
422.48 -
Molecular formula
C27H22N2O3 -
PubChem identifier
25223366 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
COc1ccc(cc1)C2C=3C(=O)CC(CC=3OC(N)=C2C#N)c5cccc4ccccc45 -
Source
Synthetic
-
Research areas
