Monosodium urate, Pro-inflammatory agent (ab144305)
Key features and details
- Pro-inflammatory agent
- CAS Number: 1198-77-2
- Soluble in 1 N NaOH to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Monosodium urate, Pro-inflammatory agent -
Description
Pro-inflammatory agent -
Biological description
Pro-inflammatory agent. induces Syk and PI3K activation. Induces phagocytosis, and IL-1β production. Activates TRPV1 and induces mast cell degranulation. Induces inflammation and algesic effects in vivo. -
CAS Number
1198-77-2 -
Chemical structure
Properties
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Chemical name
2,8-Dioxo-3,7,8,9-tetrahydro-2H-purin-6-olate sodium salt -
Molecular weight
190.09 -
Molecular formula
C5H3N4NaO3 -
PubChem identifier
23697816 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 1 N NaOH to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C1NC=2NC(=O)N=C(O[Na])C=2N1 -
Source
Synthetic
