ML 204, TRPC4 blocker (ab269883)
Key features and details
- Selective TRPC4 channel blocker
- CAS Number: 5465-86-1
- Soluble in DMSO to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ML 204, TRPC4 blocker -
Description
Selective TRPC4 channel blocker -
Biological description
Selective TRPC4 channel blocker (IC50 = 0.96 (fluorescence assay) - 2.6 μM (electrophysiological assay)). Selective versus TRPC6 (19-fold) and TRPC5 (9-fold). Essentially inactive at TRPV1, TRPV3, TRPA1 and TRPM8 channels at concentrations up to 22 μM.
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CAS Number
5465-86-1 -
Chemical structure
Properties
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Chemical name
4-Methyl-2-(1-piperidinyl)quinoline -
Molecular weight
226.32 -
Molecular formula
C15H18N2 -
PubChem identifier
230710 -
Storage instructions
Shipped at Room Temperature. Store at -20°C. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 75 mM -
Handling
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC(=NC2=CC=CC=C12)N3CCCCC3 -
Source
Synthetic
Images
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Chemical Structure - ML 204, TRPC4 blocker (ab269883)
Chemical structure of ML 204, TRPC4 blocker, 5465-86-1
