Mitochondrial Staining Reagent - NIR - Cytopainter (ab176833)
Overview
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Product name
Mitochondrial Staining Reagent - NIR - Cytopainter
See all Mitochondria kits -
Sample type
Adherent cells, Suspension cells -
Assay type
Cell-based (qualitative) -
Species reactivity
Reacts with: Mammals, Other species -
Product overview
Abcam's Mitochondrial Staining Reagent - NIR | Cytopainter (ab176833) is part of a series of new fluorogenic probes to label mitochondria of live cells. The proprietary mitochondria dye selectively accumulates in mitochondria probably via the mitochondrial membrane potential gradient. The mitochondrial indicator is a hydrophobic compound that easily permeates intact live cells and becomes trapped in mitochondria after it gets into cells. The fluorescent mitochondrial indicator is retained in mitochondria for a long time since it carries a cell-retaining group. This key feature significantly increases the staining efficiency; make it useful for a variety of studies, including cell adhesion, chemotaxis, multidrug resistance, cell viability, apoptosis and cytotoxicity.
Review other dyes and kits for mitochondrial staining, or the live cell staining fluorescent dyes guide
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Notes
Mitochondria are membrane-enclosed organelles found in most eukaryotic cells. Mitochondria are sometimes described as “cellular power plants” because they generate most of the cellular supply of ATP. In addition to supplying cellular energy, mitochondria are involved in a range of other processes, such as signaling, cellular differentiation, cell death, as well as the control of the cell cycle and cell growth. Mitochondria have been implicated in several human diseases, including mitochondrial disorders and cardiac dysfunction, and may play a role in the aging process. Although most of a cellular DNA is contained in the cell nucleus, the mitochondrion has its own independent genome.
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Platform
Fluorescence microscope
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 500 tests CytoPainter MitoNIR Indicator Reagent 1 x 500 tests -
Research areas
Images
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HeLa cells stained with CytoPainter MitoNIR Indicator Reagent (ab176833)
HeLa cells mitochondria were stained with Abcam's CytoPainter MitoNIR Indicator Reagent (ab176833), and nuclei were stained with Hoechst 33342 in a Costar black 96-well plate.
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Excitation and Emission spectra of Abcam's CytoPainter MitoNIR Indicator Reagent (ab176833)
