MI 2, MALT1 inhibitor (ab145047)
Key features and details
- Cell-permeable, irreversible MALT1 inhibitor
- CAS Number: 1047953-91-2
- Purity: > 98%
- Soluble in ethanol to 50 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
MI 2, MALT1 inhibitor -
Description
Cell-permeable, irreversible MALT1 inhibitor -
Biological description
Cell-permeable, irreversible MALT1 inhibitor (IC50 = 5.8 µM). Suppresses protease function, decreases NF-κB activity and inhibits cell proliferation. Antitumor agent. Active in vitro, in vivo and ex vivo.
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Purity
> 98% -
CAS Number
1047953-91-2 -
Chemical structure
Properties
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Chemical name
2-Chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl]phenyl]acetamide -
Molecular weight
455.73 -
Molecular formula
C19H17Cl3N4O3 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 50 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
ClCC(=O)Nc1ccc(cc1)n3nc(nc3c2ccc(Cl)c(Cl)c2)OCCOC -
Source
Synthetic
