Metyrapone, cytochrome P450 inhibitor. Blocks cortisol synthesis. (ab144618)
Key features and details
- Selective cytochrome P450 inhibitor. Blocks cortisol synthesis.
- CAS Number: 54-36-4
- Purity: > 98%
- Soluble in DMSO to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Metyrapone, cytochrome P450 inhibitor. Blocks cortisol synthesis. -
Description
Selective cytochrome P450 inhibitor. Blocks cortisol synthesis. -
Biological description
Selective cytochrome P450 inhibitor (IC50 = 1 μM). Blocks cortisol synthesis in vitro and in vivo. Neuroprotective. Cell and blood-brain barrier permeable. -
Purity
> 98% -
CAS Number
54-36-4 -
Chemical structure
Properties
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Chemical name
2-Methyl-1,2-di-3-pyridinyl-1-propanone -
Molecular weight
226.27 -
Molecular formula
C14H14N2O -
PubChem identifier
4174 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)(C1=CN=CC=C1)C(=O)C2=CN=CC=C2 -
Source
Synthetic
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Research areas