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Methyl Arachidonyl Fluorophosphonate, irreversible cPLA2 and iPLA2 inhibitor (ab141763)

Key features and details

  • Selective, active site directed, irreversible cPLA2 and iPLA2 inhibitor. Potent FAAH inhibitor.
  • CAS Number: 188404-10-6
  • Purity: > 98%
  • Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Form / State: Liquid
  • Source: Synthetic

Overview

  • Product name

    Methyl Arachidonyl Fluorophosphonate, irreversible cPLA2 and iPLA2 inhibitor

  • Description

    Selective, active site directed, irreversible cPLA2 and iPLA2 inhibitor. Potent FAAH inhibitor.

  • Biological description

    Selective, active site directed, irreversible cPLA2 and iPLA2 inhibitor. Potent FAAH inhibitor (IC50 = 2.5 nM). Inhibits A23187 (ab120287, ab142245, ab142244)-induced arachidonic acid release from platelets (IC50 = 600 nM). Potent, irreversible anandamide amidase inhibitor. Prolongs and intensifies aerobic exercise-induced antinociceptive effects in vivo.

  • Purity

    > 98%

  • CAS Number

    188404-10-6

  • Chemical structure

    Chemical Structure

Properties

Images

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