Methazolamide, Carbonic anhydrase inhibitor (ab145585)
Key features and details
- Potent, cell-permeable carbonic anhydrase inhibitor
- CAS Number: 554-57-4
- Purity: > 98%
- Soluble in DMSO to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Methazolamide, Carbonic anhydrase inhibitor -
Description
Potent, cell-permeable carbonic anhydrase inhibitor -
Biological description
Potent, cell-permeable carbonic anhydrase inhibitor (Ki values are 50, 14 and 36 nM for hCA I, hCA II and bCA IV isoforms respectively). Shows diuretic and antidiabetic effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
554-57-4 -
Chemical structure
Properties
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Chemical name
N-(3-Methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide -
Molecular weight
236.27 -
Molecular formula
C5H8N4O3S2 -
PubChem identifier
4100 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C -
Source
Synthetic
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Research areas