Manidipine dihydrochloride, calcium channel blocker (ab142317)
Key features and details
- Potent calcium channel blocker
- CAS Number: 89226-75-5
- Purity: > 98%
- Soluble in DMSO, water and ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Manidipine dihydrochloride, calcium channel blocker -
Description
Potent calcium channel blocker -
Biological description
Potent calcium channel blocker (IC50 = 2.6 nM). Suppresses proliferation and stimulates glycosaminoglycan synthesis in vitro. Antihypertensive agent. Orally active. Active in vitro and in vivo. -
Purity
> 98% -
CAS Number
89226-75-5 -
Chemical structure
Properties
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Chemical name
5-O-[2-(4-Benzhydrylpiperazin-1-yl)ethyl]-3-O-methyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochloride -
Molecular weight
683.62 -
Molecular formula
C35H38N4O6.2HCl -
PubChem identifier
150762 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO, water and ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(C(C(=C(N1)C)C(=O)OCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC.Cl.Cl -
Source
Synthetic
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Research areas
