Zonisamide, Non-selective Na+ / Ca2+ channel blocker (ab120369)
Key features and details
- Non-selective Na+ / Ca2+ channel blocker
- CAS Number: 68291-97-4
- Purity: > 99%
- Soluble in water to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Zonisamide, Non-selective Na+ / Ca2+ channel blocker -
Description
Non-selective Na+ / Ca2+ channel blocker -
Alternative names
- AD810
- CI912
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Biological description
Broad spectrum antiepileptic with multiple mechanisms of action. Blocks voltage-sensitive Na+ and T-type Ca2+ channels and stimulates BKCa channels. Modulates GABA, glutamate, cholinergic and monoamine neurotransmission. Exhibits free-radical scavenging properties.
Also available in simple stock solutions (ab146711) - add 1 ml of water to get an exact, ready-to-use concentration. -
Purity
> 99% -
CAS Number
68291-97-4 -
Chemical structure
Properties
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Chemical name
1,2-Benzisoxazole-3-methanesulfonamide -
Molecular weight
212.22 -
Molecular formula
C8H8N2O3S -
PubChem identifier
5734 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 10 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
NS(=O)(=O)Cc2noc1ccccc12 -
Source
Synthetic
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Research areas