LY2940680 (Taladegib) (ab269874)
Key features and details
- Potent Hedgehog signaling pathway inhibitor
- CAS Number: 1258861-20-9
- Soluble in DMSO to 100 mM with ultrasonic and warming
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
LY2940680 (Taladegib) -
Description
Potent Hedgehog signaling pathway inhibitor -
Alternative names
- Taladegib
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Biological description
Potent Hedgehog signaling pathway inhibitor. Smoothened antagonist. Inhibits growth of cancer cell lines containing a disease-relevant Smoothened gene mutation. Has anti-tumor activity in animal models.
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CAS Number
1258861-20-9 -
Chemical structure
Properties
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Chemical name
4-Fluoro-N-methyl-N-[1-[4-(1-methyl-1H-pyrazol-5-yl)-1-phthalazinyl]-4- piperidinyl]-2-(trifluoromethyl)benzamide -
Molecular weight
512.50 -
Molecular formula
C26H24F4N6O -
PubChem identifier
49848070 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Soluble in DMSO to 100 mM with ultrasonic and warming -
Handling
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN1C(=CC=N1)C2=NN=C(C3=CC=CC=C32)N4CCC(CC4)N(C)C(=O)C5=C(C=C(C=C5)F)C(F)(F)F -
Source
Synthetic
Images
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Chemical Structure - LY2940680 (Taladegib) (ab269874)
Chemical structure of LY2940680 (Taladegib), 1258861-20-9
