LY 456236, mGlu1 non competitive antagonist (ab120201)
Key features and details
- mGlu1 non competitive antagonist
- CAS Number: 338736-46-2
- Purity: > 99%
- Soluble in DMSO to 50 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
LY 456236, mGlu1 non competitive antagonist -
Description
mGlu1 non competitive antagonist -
Biological description
Selective non-competitive antagonist at the mGlu1 receptor. Inhibits agonist induced phosphoinositide hydrolysis in vitro (IC50 = 140 nM) and in vivo following systemic administration.
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Purity
> 99% -
CAS Number
338736-46-2 -
Chemical structure
Properties
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Chemical name
(4-Methoxyphenyl)-(6-methoxy-quinazolin-4-yl)amine hydrochloride -
Molecular weight
317.77 -
Molecular formula
C16H15N3O2.HCl -
PubChem identifier
9926998 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.COc1ccc(cc1)Nc3ncnc2ccc(cc23)OC -
Source
Synthetic
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Research areas