cis-PPDA, GluN2C/GluN2D NMDA antagonist (ab120047)
Key features and details
- GluN2C/GluN2D (formerly NR2C/NR2D) NMDA antagonist
- CAS Number: 684283-16-7
- Purity: > 98%
- Soluble in 2 eq. NaOH to 50 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
cis-PPDA, GluN2C/GluN2D NMDA antagonist -
Description
GluN2C/GluN2D (formerly NR2C/NR2D) NMDA antagonist -
Biological description
Potent GluN2C/GluN2D (formerly NR2C / NR2D)-preferring NMDA receptor antagonist. (Ki values for recombinant rat receptors are 0.096 (NR2C), 0.125 (NR2D), 0.55 (NR2A) and 0.31 μM (NR2B)).
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Purity
> 98% -
CAS Number
684283-16-7 -
Chemical structure
Properties
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Chemical name
(2R*,3S*)-1-(Phenanthrenyl-2-carbonyl)piperazine-2,3-dicarboxylic acid -
Molecular weight
378.38 -
Molecular formula
C21H18N2O5 -
PubChem identifier
10293029 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 2 eq. NaOH to 50 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(c2cc3ccc1ccccc1c3cc2)N4CCNC(C(=O)O)C4C(=O)O -
Source
Synthetic
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Research areas
