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Signal Transduction Growth Factors/Hormones TGF

LY 364947, ATP-competitive TGFbeta receptor kinase I inhibitor (ab141890)

Price and availability

87 110 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Potent, selective ATP-competitive TGFβ receptor kinase I inhibitor
  • CAS Number: 396129-53-6
  • Purity: > 98%
  • Soluble in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    LY 364947, ATP-competitive TGFbeta receptor kinase I inhibitor
  • Description

    Potent, selective ATP-competitive TGFβ receptor kinase I inhibitor
  • Alternative names

    • HTS 466284
    • TGF-beta inhibitor
  • Purity

    > 98%
  • CAS Number

    396129-53-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]quinoline
  • Molecular weight

    272.30
  • Molecular formula

    C17H12N4
  • PubChem identifier

    447966
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC=C2C(=C1)C(=CC=N2)C3=C(NN=C3)C4=CC=CC=N4
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Angiogenesis
    • Growth Factors
    • TGF
    • Signal Transduction
    • Protein Phosphorylation
    • Ser / Thr Kinases
    • MAPK Pathway
    • Signal Transduction
    • Protein Phosphorylation
    • Ser / Thr Kinases
    • Other Kinases
    • Signal Transduction
    • Growth Factors/Hormones
    • TGF
    • Signal Transduction
    • Growth Factors/Hormones
    • Hormones
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • SMADs
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Corticoid
    • Stem Cells
    • Signaling Pathways
    • TGF beta
    • Surface Molecules
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Transcription Factors
    • Cancer
    • Growth factors
    • TGF
    • Immunology
    • Innate Immunity
    • TLR Signaling
    • Cancer
    • Cancer Metabolism
    • Response to hypoxia
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
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    • Pathways and Processes
    • Metabolism processes
    • Hypoxia
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    • Pharmacology
    • Receptors & Transporters
    • Enzyme-Linked Receptors
    • Cytokine receptors
    • Cytokines
    • Biochemicals
    • Pharmacology
    • Signaling
    • Stem Cells
    • Growth factors

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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