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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

LY 294002 (DMSO solution), PI3-kinase inhibitor (ab146593)

Price and availability

80 409 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • PI3-kinase inhibitor
  • CAS Number: 154447-36-6
  • Purity: > 99%
  • Supplied in DMSO (10 mM)
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    LY 294002 (DMSO solution), PI3-kinase inhibitor
  • Description

    PI3-kinase inhibitor
  • Biological description

    A highly selective inhibitor of phosphatidylinositol 3-kinase (IC50 = 1.4 μM). Selective over a range of other kinases including protein kinase C, protein kinase A, MAPK and PI4- kinase (IC50 > 50 μM).

    Also available as a solid (ab120243).

  • Purity

    > 99%
  • CAS Number

    154447-36-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-(4-Morpholinyl)-8-phenyl-1(4H)-benzopyran-4-one
  • Molecular weight

    307.35
  • Molecular formula

    C19H17NO3
  • PubChem identifier

    3973
  • Storage instructions

    Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
  • Solubility overview

    Supplied in DMSO (10 mM)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    O=C2C=C(Oc1c(cccc12)c3ccccc3)N4CCOCC4
  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Cell Cycle
    • Kinases/Phosphatases
    • Other
    • Cell Biology
    • Cell Cycle
    • Cell Cycle Inhibitors
    • Other
    • Cell Biology
    • Cell Cycle
    • Cell Division
    • Spindle
    • Neuroscience
    • Neurology process
    • Notch Pathway
    • Neuroscience
    • Neurotransmission
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    • GPCR
    • Serotonin Receptors
    • Epigenetics and Nuclear Signaling
    • Chromatin Binding Proteins
    • Methyl Lysine
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Damage & Repair
    • Non Homol. End Joining
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Damage & Repair
    • DNA Damage Response
    • DNA Damage Recognition
    • Signal Transduction
    • Protein Phosphorylation
    • Ser / Thr Kinases
    • Other Kinases
    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • Lipid Kinases
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR
    • Neuroscience
    • Neurology process
    • Metabolism
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Cancer susceptibility
    • Proto-oncogenes
    • Stem Cells
    • Signaling Pathways
    • Wnt
    • Cytoplasmic
    • Epigenetics and Nuclear Signaling
    • Cell cycle
    • Kinases/Phosphatases
    • Other
    • Stem Cells
    • Signaling Pathways
    • Notch
    • Cytoplasmic
    • Stem Cells
    • Hematopoietic Progenitors
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    • Cell cycle inhibitors
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