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LP-44, 5-HT7 agonist (ab120593)

Price and availability

469 056 ₸

Availability

Order now and get it on Tuesday March 09, 2021

Key features and details

  • Highly potent, selective 5-HT7 agonist
  • CAS Number: 824958-12-5
  • Purity: > 99%
  • Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    LP-44, 5-HT7 agonist
  • Description

    Highly potent, selective 5-HT7 agonist
  • Biological description

    Highly potent, selective 5-HT7 agonist (Ki = 0.22 nM). Shows >200 and >1000-fold selectivity over 5-HT1A and 5-HT2A receptors, respectively. Supresses REM sleep.

  • Purity

    > 99%
  • CAS Number

    824958-12-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-[2-(Methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-1-piperazinehexanamide hydrochloride
  • Molecular weight

    488.13
  • Molecular formula

    C27H37N3OS.HCl
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Serotonin Receptors
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Serotonin
    • 5-HT7
    • Agonists
    • Biochemicals
    • Research Area
    • Depression
    • Serotonin
    • 5-HT7
    • Agonists
    • Biochemicals
    • Research Area
    • Obesity
    • Serotonin
    • 5-HT7
    • Agonists
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Serotonin
    • 5-HT7
    • Agonists
    • Biochemicals
    • Research Area
    • Stress / Anxiety
    • Serotonin
    • 5-HT7
    • Agonists

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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