Lixisenatide, peptidic GLP-1 receptor agonist (ab231358)
Key features and details
- Short acting, potent and selective peptidic GLP-1 receptor agonist
- CAS Number: 320367-13-3
- Purity: > 99%
soluble in water to 100 mg/mL .
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Lixisenatide, peptidic GLP-1 receptor agonist -
Description
Short acting, potent and selective peptidic GLP-1 receptor agonist -
Biological description
Lixisenatide is a short acting, potent and selective short peptide-based GLP-1 receptor agonist. The in vivo half-life is 2-4 hours. Displays an IC50 of 1.4 nM at the human GLP-1 receptor in in vitro binding assays. Produces a dose-dependent reduction in blood glucose levels in animal models. Preserves the pancreatic responsiveness of diabetic animals.
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Purity
> 99% -
CAS Number
320367-13-3 -
Chemical structure
Properties
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Molecular weight
4858.56 -
Molecular formula
C215H347N61O65S -
Sequence
HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPSKKKKKK-NH2 (Modifications: C-terminal amide) -
PubChem identifier
90472060 -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Solubility overview
soluble in water to 100 mg/mL .
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Source
Synthetic
