Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Endogenous MDM2 and MDM4 selective inhibitor. Detergent.
CAS Number: 434-13-9
Purity: > 97%
Soluble in ethanol and in DMSO
Form / State: Solid
Source: Synthetic

Product name

Lithocholic acid, endogenous MDM2 and MDM4 selective inhibitor
Description

Endogenous MDM2 and MDM4 selective inhibitor. Detergent.
Biological description

Endogenous MDM2 and MDM4 selective inhibitor. Detergent. Solubilizes dietary fats for absorption. Increases p53 and cyclin D1 promoter activity and endogenous p53 and cyclin D1 expression and apoptosis. Shows cancer cell selective antiproliferative effects. Shows cholagogue and choleretic effects in vivo.
Purity

> 97%
CAS Number

434-13-9
Chemical structure

Chemical name

(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
Molecular weight

376.57
Molecular formula

C₂₄H₄₀O₃
PubChem identifier

9903
Storage instructions

Store at Room Temperature. The product can be stored for up to 12 months.
Solubility overview

Soluble in ethanol and in DMSO
Handling

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
SMILES

CC(CCC(=O)O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C
Source

Synthetic
Research areas

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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