Lithocholic acid, endogenous MDM2 and MDM4 selective inhibitor (ab145598)
Key features and details
- Endogenous MDM2 and MDM4 selective inhibitor. Detergent.
- CAS Number: 434-13-9
- Purity: > 97%
- Soluble in ethanol and in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Lithocholic acid, endogenous MDM2 and MDM4 selective inhibitor -
Description
Endogenous MDM2 and MDM4 selective inhibitor. Detergent. -
Biological description
Endogenous MDM2 and MDM4 selective inhibitor. Detergent. Solubilizes dietary fats for absorption. Increases p53 and cyclin D1 promoter activity and endogenous p53 and cyclin D1 expression and apoptosis. Shows cancer cell selective antiproliferative effects. Shows cholagogue and choleretic effects in vivo. -
Purity
> 97% -
CAS Number
434-13-9 -
Chemical structure
Properties
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Chemical name
(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid -
Molecular weight
376.57 -
Molecular formula
C24H40O3 -
PubChem identifier
9903 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(CCC(=O)O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C -
Source
Synthetic
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Research areas
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Vitamin D Receptor
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors