Leukotriene E4, CysLT1 and CysLT2 agonist (ab141690)
Key features and details
- Partial, selective CysLT1 and CysLT2 agonist
- CAS Number: 75715-89-8
- Purity: > 98%
- Supplied in methanol/ammonium acetate buffer, 70/30, pH 5.6 (50 µg/ml)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
Leukotriene E4, CysLT1 and CysLT2 agonist -
Description
Partial, selective CysLT1 and CysLT2 agonist -
Biological description
Partial, selective CysLT1 and CysLT2 agonist (EC50 values are 55.9 and 59 nM, respectively). Induces hypotension and bronchoconstriction. Active in vivo and in vitro. -
Purity
> 98% -
CAS Number
75715-89-8 -
Chemical structure
Properties
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Chemical name
(5S,6R,7E,9E,11Z,14Z)-6-(2-Amino-2-carboxyethyl)sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid -
Molecular weight
439.61 -
Molecular formula
C23H37NO5S -
PubChem identifier
5280749 -
Storage instructions
Shipped at 4°C. Store at -80°C. -
Solubility overview
Supplied in methanol/ammonium acetate buffer, 70/30, pH 5.6 (50 µg/ml) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)O)N -
Source
Synthetic
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Research areas
