L-Glutamate, excitatory neurotransmitter (ab120049)
Key features and details
- Excitatory neurotransmitter
- CAS Number: 56-86-0
- Purity: > 99%
- Soluble in 1 eq. NaOH to 100 mM and in water to 25mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
L-Glutamate, excitatory neurotransmitter -
Description
Excitatory neurotransmitter -
Biological description
Major excitatory neurotransmitter. Acts at glutamate receptors. Active in vivo.
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Purity
> 99% -
CAS Number
56-86-0 -
Chemical structure
Properties
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Chemical name
(S)-2-Aminopentanedioic acid -
Molecular weight
147.13 -
Molecular formula
C5H9NO4 -
PubChem identifier
33032 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 1 eq. NaOH to 100 mM and in water to 25mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
OC(=O)CC[C@H](N)C(=O)O -
Source
Synthetic
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Research areas
Images
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Functional Studies - L-Glutamate, excitatory neurotransmitter (ab120049)ab55051 staining GABA B receptor 1 in SK-N-SH cells treated with L-Glutamate (ab120049), by ICC/IF. Internalization of GABA B receptor 1 correlates with increased concentration of L-Glutamate, as described in literature.
The cells were incubated at 37°C for 30 minutes in media containing different concentrations of ab120049 (L-Glutamate) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab55051 (1 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-mouse polyclonal antibody (ab96879) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.