L-655,240, Thromboxane A2 receptor antagonist (ab120946)
Key features and details
- Potent thromboxane A2 receptor antagonist
- CAS Number: 103253-15-2
- Purity: > 98%
- Soluble in ethanol to 50 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
L-655,240, Thromboxane A2 receptor antagonist -
Description
Potent thromboxane A2 receptor antagonist -
Biological description
Potent thromboxane A2 receptor antagonist (IC50 = 7 nM). Blocks TP-mediated bronchoconstriction in vivo and platelet aggregation ex vivo. Orally active in vivo. -
Purity
> 98% -
CAS Number
103253-15-2 -
Chemical structure
Properties
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Chemical name
1-[(4-Chlorophenyl)methyl]-5-fluoro-α,α,3-trimethyl-1H-indole-2-propanoic acid -
Molecular weight
373.85 -
Molecular formula
C21H21ClFNO2 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 50 mM and in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
ClC1=CC=C(CN2C(CC(C)(C)C(O)=O)=C(C)C3=CC(F)=CC=C32)C=C1 -
Source
Synthetic
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Research areas
