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Kanamycin sulfate (aqueous), aminoglycoside antibiotic agent (ab146574)

Key features and details

  • Aminoglycoside antibiotic agent.
  • CAS Number: 25389-94-0
  • Supplied in water (30 mg/ml)
  • Form / State: Solid
  • Source: Synthetic

Overview

  • Product name

    Kanamycin sulfate (aqueous), aminoglycoside antibiotic agent

  • Description

    Aminoglycoside antibiotic agent.

  • Alternative names

    • Kanamycin A (sulfate)
    • kanamycin A sulfate
    • kanamycin acid sulphate
    • Ophtalmokalixan

  • Biological description

    Aminoglycoside antibiotic agent effective against Gram-negative and Gram-positive bacteria and mycoplasma. Originally purified from the bacterium Streptomyces kanamyceticus. Binds to the bacterial 30S ribosomal subunit, inhibits translocation, and elicits miscoding. Often used to select for bacteria which have been successfully transformed with a plasmid conferring kanamycin resistance.


     

  • CAS Number

    25389-94-0

  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2R,3S,4S,5R,6R)-2-(Aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol sulfate

  • Molecular weight

    582.58

  • Molecular formula

    C18H36N4O11.H2SO4

  • PubChem identifier

    441374

  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

  • Solubility overview

    Supplied in water (30 mg/ml)

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N.OS(=O)(=O)O

  • Source

    Synthetic

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