Kainic acid (mM/ml), Prototypic kainate receptor agonist (ab144490)
Key features and details
- Prototypic kainate receptor agonist. 1 ml water soluble pack.
- CAS Number: 487-79-6
- Purity: > 99%
- Soluble in 1ml of water to give specified mM/ml concentration
- Form / State: Solid
- Source: Digenea simplex
Overview
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Product name
Kainic acid (mM/ml), Prototypic kainate receptor agonist -
Description
Prototypic kainate receptor agonist. 1 ml water soluble pack. -
Alternative names
- Kainate
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Biological description
Prototypic agonist at the kainate class of ionotropic glutamate receptors. Potent excitant and neurotoxin, used to model epilepsy and neurodegenerative states.
Soluble in 1 ml water to give specified mM/ml concentration. Find out more. -
Purity
> 99% -
CAS Number
487-79-6 -
Chemical structure
Properties
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Chemical name
(2S,3S,4S)-3-(Carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid -
Molecular weight
213.23 -
Molecular formula
C10H15NO4 -
PubChem identifier
10255 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 1ml of water to give specified mM/ml concentration -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=C)[C@H]1CN[C@@H]([C@H]1CC(=O)O)C(=O)O -
Source
Digenea simplex
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Research areas
Images
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Immunocytochemistry/ Immunofluorescence - Kainic acid (mM/ml), Prototypic kainate receptor agonist (ab144490) Image from Menteyne, A et al., PloS one., 4(8): e6770. Fig 1A.; doi: 10.1371/journal.pone.0006770 Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/
Immunocytochemistry/ Immunofluorescence analysis of microglial cells in the stratum radiatum of the CA1 region of the hippocampus of CX3CR1egfp/+ mice in control conditions (left) or 48 hours after status epilepticus (SE) induced by intra-peritoneal injection of kainate (right). Each image is a maximum intensity z-projection of 31 confocal slices for a total thickness of 12 µm.