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Immunology Innate Immunity Macrophage / Inflamm.

Ibuprofen, NSAID (ab141553)

Key features and details

  • A nonsteroidal anti-inflammatory drug (NSAID). COX inhibitor.
  • CAS Number: 15687-27-1
  • Purity: > 99%
  • Soluble in ethanol to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Ibuprofen, NSAID
  • Description

    A nonsteroidal anti-inflammatory drug (NSAID). COX inhibitor.
  • Biological description

    A nonsteroidal anti-inflammatory drug (NSAID). Non-selective inhibitor of COX-1 and COX-2 (IC50 values are 12 and 80 µM respectively). Inhibits thromboxane B2 release (IC50 = 1.27 µM) and anandamide metabolism (IC50 = 400 µM).
  • Purity

    > 99%
  • CAS Number

    15687-27-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-[4-(2-Methylpropyl)phenyl]propanoic acid
  • Molecular weight

    206.30
  • Molecular formula

    C13H18O2
  • PubChem identifier

    3672
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Refer to SDS for further information

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)CC1=CC=C(C=C1)C(C)C(=O)O
  • Source

    Synthetic

  • Research areas

    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Cardiovascular
    • Blood
    • Serum Proteins
    • Cardiovascular
    • Blood
    • Platelets
    • Cardiovascular
    • Blood
    • Other
    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Cholesterol Metabolism
    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • Prostaglandins
    • Cancer
    • Tumor biomarkers
    • Other
    • Cardiovascular
    • Atherosclerosis
    • Lipoprotein metabolism
    • Cancer
    • Cancer Metabolism
    • Metabolic signaling pathway
    • Hormone biosynthesis
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Cyclooxygenase
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Lipid signaling
    • Cyclooxygenase
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Cholesterol Metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipoprotein metabolism
    • Metabolism
    • Pathways and Processes
    • Redox metabolism
    • Oxidative stress
    • Metabolism
    • Pathways and Processes
    • Endocrine metabolism
    • Hormone biosynthesis
    • Metabolism
    • Types of disease
    • Heart disease
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Immunomodulators & Immunosuppressants

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