Astana Biomed Group, an authorized Abcam distributor in Central Asia

Human UCP2 knockout HEK293T cell pellet (ab279189)

Overview

  • Product name

    Human UCP2 knockout HEK293T cell pellet
    See all UCP2 kits

  • Product overview

    Abcam’s knockout cell pellets give you access to native proteins, without the need to culture cells. Our knockout cell pellets are prepared from our single-gene knockout cell lines and provide an additional offering to our cell lysates.

    Cells are snap-frozen to provide high quality pellets that are suitable for extraction with alternative lysis buffers or for preparation of lysates from subcellular fractions. Our knockout cell pellets are suitable for a variety of applications, including PCR, gene expression profiling and DNA library preparation.

  • Parental Cell Line

    HEK293T

  • Organism

    Human

  • Mutation description

    Knockout achieved by using CRISPR/Cas9, Homozygous: 7 bp deletion in exon 3.

  • Passage number

  • Knockout validation

    Sanger Sequencing

  • Notes

    Pellet size: 5 million cells/vial.

    This product is subject to limited use licenses from The Broad Institute and ERS Genomics Limited, and is developed with patented technology. For full details of the limited use licenses and relevant patents please refer to our limited use license and patent pages.

Properties

Target

  • Function

    UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.

  • Tissue specificity

    Widely expressed in adult human tissues, including tissues rich in macrophages. Most expressed in white adipose tissue and skeletal muscle.

  • Sequence similarities

    Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.

  • Cellular localization

    Mitochondrion inner membrane.
  • Information by UniProt

  • Alternative names

    • BMIQ4
    • Mitochondrial uncoupling protein 2
    • SLC25A8
    • Solute carrier family 25 member 8
    • UCP 2
    • ucp2
    • UCP2_HUMAN
    • UCPH
    • Uncoupling protein 2
    • Uncoupling protein 2 mitochondrial proton carrier
    see all

Properties

Images

  • Sanger Sequencing - Human UCP2 knockout HEK293T cell pellet (ab279189)
    Sanger Sequencing - Human UCP2 knockout HEK293T cell pellet (ab279189)
    Homozygous: 7 bp deletion in exon 3

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Clear all

Recently viewed products

Sign up