Human TSLP ELISA Kit (ab155444)
Key features and details
- Sensitivity: 3 pg/ml
- Range: 3.3 pg/ml - 800 pg/ml
- Sample type: Cell culture supernatant, Plasma, Serum
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Human
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 1 x 96 tests 200X HRP-Streptavidin Concentrate 1 x 200µl 20X Wash Buffer Concentrate 1 x 25ml 5X Assay Diluent B 1 x 15ml 5X Assay Diluent D 1 x 15ml Detection Antibody TSLP : biotinylated anti-human TSLP 2 vials Stop Solution 1 x 8ml TMB One-Step Substrate Reagent 1 x 12ml TSLP Standard Human (recombinant) (lyophilized) 2 vials TSLP-coated Microplate 1 unit -
Research areas
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Relevance
The TSLP gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. This mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, chronic obstructive pulmonary disease and allergic inflammation. The protein is therefore considered a potential therapeutic target for the treatment of these diseases. Alternative splicing of this gene results in multiple transcript variants. -
Cellular localization
Secreted -
Alternative names
- Thymic stromal lymphopoietin
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Database links
- Entrez Gene: 85480 Human
- Omim: 607003 Human
- SwissProt: Q969D9 Human
- Unigene: 389874 Human
Images
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Typical Standard Curve
Representative standard curve using ab155444 - Assay Diluent D.
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Typical Standard CurveRepresentative standard curve using ab155444 - Assay Diluent B.
