Human Sex Hormone Binding Globulin/SHBG ELISA Kit (ab213824)
Key features and details
- Sensitivity: 0.001 nmol/L
- Range: 0.031 nmol/L - 2 nmol/L
- Sample type: Cell culture supernatant, Cell Lysate, EDTA Plasma, Hep Plasma, Serum, Tissue Homogenate
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Human
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components Identifier 1 x 96 tests ABC Diluent Buffer Blue Cap 1 x 12ml Adhesive Plate Seal 4 units Antibody Diluent Buffer Green Cap 1 x 12ml Anti-Human SHBG coated Microplate (12 x 8 wells) 1 unit Avidin-Biotin-Peroxidase Complex (ABC) 1 x 100µl Biotinylated anti-Human SHBG antibody 1 x 130µl Lyophilized recombinant Human SHBG standard 2 vials Sample Diluent Buffer Green Cap 1 x 30ml TMB Color Developing Agent Black Cap 1 x 10ml TMB Stop Solution Yellow Cap 1 x 10ml -
Research areas
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Function
Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. -
Tissue specificity
Isoform 1 and isoform 2 are present in liver and testis. -
Sequence similarities
Contains 2 laminin G-like domains. -
Cellular localization
Secreted. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis. - Information by UniProt
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Alternative names
- ABP
- Androgen binding protein
- SBP
see all -
Database links
- Entrez Gene: 6462 Human
- Omim: 182205 Human
- SwissProt: P04278 Human
- Unigene: 632235 Human
Images
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Human Sex Hormone Binding Globulin/SHBG ELISA Kit (ab213824) Standard Curve.
Human Sex Hormone Binding Globulin/SHBG ELISA Kit (ab213824) Standard Curve.
