Human NGF R ELISA Kit (CD271) (ab155436)
Key features and details
- Sensitivity: 80 pg/ml
- Range: 0.082 ng/ml - 20 ng/ml
- Sample type: Cell culture supernatant, Plasma, Serum
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Human
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 1 x 96 tests 20X Wash Buffer Concentrate 1 x 25ml 5X Assay Diluent B 1 x 15ml 500X HRP-Streptavidin Concentrate 1 x 200µl Assay Diluent C 1 x 30ml Biotinylated anti-Human NGF R 2 vials NGF R Microplate (12 x 8 wells) 1 unit Recombinant Human NGF R Standard (lyophilized) 2 vials Stop Solution 1 x 8ml TMB One-Step Substrate Reagent 1 x 12ml -
Research areas
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Relevance
Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver. -
Cellular localization
Membrane; Single-pass type I membrane protein. -
Alternative names
- CD271
- Gp80-LNGFR
- Low affinity neurotrophin receptor p75NTR
see all -
Database links
- Entrez Gene: 4804 Human
- Omim: 162010 Human
- SwissProt: P08138 Human
Images
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NGF R (CD271) Human ELISA kit
Representative standard curve using ab155436